Gene name:
Abcb1(Mdr1;Mdr1b;Pgy1);
Protein name:
Multidrug resistance protein 1;
Alternative:
P-glycoprotein 1;ATP-binding cassette sub-family B member 1;
CD:
CD243;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with PSMB5.
Function:
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MEFEEGLNGR | ADKNFSKMGK | KSKKEKEKKP | AVGIFGMFRY | ADWLDKLCMA |
100:
LGTLAAIIHG | TLLPLLMLVF | GYMTDSFTPS | RDPHSDRAIT | NQSEINSTHT |
150:
VSDTSLEEDM | AMYAYYYTGI | GAGVLIVAYI | QVSLWCLAAG | RQIHKIRQKF |
200:
FHAIMNQEIG | WFDVNDAGEL | NTRLTDDVSK | INDGIGDKLG | MFFQSITTFS |
250:
AGFIIGFISG | WKLTLVILAV | SPLIGLSSAM | WAKVLTSFTN | KELQAYAKAG |
300:
AVAEEVLAAI | RTVIAFGGQK | KELERYNKNL | EEAKRVGIKK | AITANISIGI |
350:
AYLLVYASYA | LAFWYGTSLV | LSNEYSIGQV | LTVFFSILLG | TFSIGHLAPN |
400:
IEAFANARGA | AYEIFKIIDN | EPSIDSFSTK | GHKPDSIMGN | LEFKNVYFNY |
450:
PSRSEVKILK | GLNLKVKSGQ | TVALVGNSGC | GKSTTVQLLQ | RLYDPIEGEV |
500:
SIDGQDIRTI | NVRYLREIIG | VVSQEPVLFA | TTIAENIRYG | RENVTMDEIE |
550:
KAVKEANAYD | FIMKLPHKFD | TLVGERGAQL | SGGQKQRIAI | ARALVRNPKI |
600:
LLLDEATSAL | DTESEAVVQA | ALDKAREGRT | TIVIAHRLST | VRNADVIAGF |
650:
DGGVIVEQGN | HEELMKEKGI | YFKLVMTQTR | GNEIEPGNNA | YESQSDTGAS |
700:
ELTSEESKSP | LIRRSIRRSI | HRRQDQERRL | SSKEDVDEDV | PMVSFWQILK |
750:
LNISEWPYLV | VGVLCAVING | CIQPVFAIVF | SKIVGVFSRD | DDHETKQRNC |
800:
NLFSLLFLVM | GMISFVTYFF | QGFTFGKAGE | ILTKRLRYMV | FKSMLRQDIS |
850:
WFDDHKNTTG | SLTTRLASDA | SNVKGAMGSR | LAVVTQNVAN | LGTGIILSLV |
900:
LVYGWQLTLL | LVVIIPLIVL | GGIIEMKLLS | GQALKDKKEL | EISGKIATEA |
950:
IENFRTVVSL | TREQKFETMY | AQSLQIPYRN | ALKKAHVFGI | TFAFTQAMIY |
1000:
FSYAACFRFG | AYLVARELMT | FENVMLVFSA | VVFGAMAAGN | TSSFAPDYAK |
1050:
AKVSASHIIG | IIEKIPEIDS | YSTEGLKPNW | LEGNVKFNGV | KFNYPTRPNI |
1100:
PVLQGLSFEV | KKGQTLRLVG | SSGCGKSTVV | QLLERFYNPM | AGTVFLDGKE |
1150:
IKQLNVQCVR | ALGIVSQEPI | LFDCSIAENI | AYGDNSRVVS | HEEIVRAARE |
1200:
ANIHQFIDSL | PEKYNTRVGD | KGTQLSGGQK | QRIAIARALV | RQPHILLLDE |
1250:
ATSALDTESE | KVVQEALDKA | REGRTCVVIA | HRLSTIQNAD | LIVVIQNGQV |
1277:
KEHGTHQQLL | AQKGIYFSMV | QAGAKRS

Vaild Sequence:
Related Databases
Uniprot:
FOR
ELISA Kit for Rat Multidrug resistance protein 1
ELISA Kit for Rat Multidrug resistance protein 1
ELISA Kit for Rat Multidrug resistance protein 1
CLIA Kit for Rat Multidrug resistance protein 1
CLIA Kit for Rat Multidrug resistance protein 1
CLIA Kit for Rat Multidrug resistance protein 1
Polyclonal Antibody for Rat Multidrug resistance protein 1
Polyclonal Antibody for Rat Multidrug resistance protein 1
Polyclonal Antibody for Rat Multidrug resistance protein 1
Monoclonal Antibody for Rat Multidrug resistance protein 1
Monoclonal Antibody for Rat Multidrug resistance protein 1
Monoclonal Antibody for Rat Multidrug resistance protein 1
Protein for Rat Multidrug resistance protein 1
Protein for Rat Multidrug resistance protein 1
Protein for Rat Multidrug resistance protein 1

R&D Technical Data
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Precision
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Recovery
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Linearity
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References
-
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]
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2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1212-1277
strain:
Sprague-Dawley.
tissue:
Liver.